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4C-seq characterization of Drosophila BEAF binding regions provides evidence for highly variable long-distance interactions between active chromatin

Chromatin organization is crucial for nuclear functions such as gene regulation, DNA replication and DNA repair. Insulator binding proteins, such as the Drosophila Boundary Element-Associated Factor (BEAF), are involved in chromatin organization. To further understand the role of BEAF, we detected c...

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Detalles Bibliográficos
Autores principales: Shrestha, Shraddha, Oh, Dong-Ha, McKowen, J. Keller, Dassanayake, Maheshi, Hart, Craig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152978/
https://www.ncbi.nlm.nih.gov/pubmed/30248133
http://dx.doi.org/10.1371/journal.pone.0203843