Resistance to FLT3 inhibitors in acute myeloid leukemia: Molecular mechanisms and resensitizing strategies

FMS-like tyrosine kinase 3 (FLT3) is classified as a type III receptor tyrosine kinase, which exerts a key role in regulation of normal hematopoiesis. FLT3 mutation is the most common genetic mutation in acute myeloid leukemia (AML) and represents an attractive therapeutic target. Targeted therapy w...

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Detalles Bibliográficos
Autores principales: Zhou, Jianbiao, Chng, Wee-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153124/
https://www.ncbi.nlm.nih.gov/pubmed/30254964
http://dx.doi.org/10.5306/wjco.v9.i5.90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153124/
https://www.ncbi.nlm.nih.gov/pubmed/30254964
http://dx.doi.org/10.5306/wjco.v9.i5.90

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