Presynaptic mGlu1 Receptors Control GABA(B) Receptors in an Antagonist-Like Manner in Mouse Cortical GABAergic and Glutamatergic Nerve Endings

Mouse cortical GABAergic synaptosomes possess presynaptic inhibitory GABA(B) autoreceptors. Accordingly, (±)baclofen (3 μM) inhibits in a CGP53423-sensitive manner the 12 mM KCl-evoked release of preloaded [(3)H]GABA. Differently, the existence of presynaptic release-regulating metabotropic glutamat...

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Detalles Bibliográficos
Autores principales: Vergassola, Matteo, Olivero, Guendalina, Cisani, Francesca, Usai, Cesare, Bossi, Simone, Puliti, Aldamaria, Pittaluga, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153310/
https://www.ncbi.nlm.nih.gov/pubmed/30279647
http://dx.doi.org/10.3389/fnmol.2018.00324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153310/
https://www.ncbi.nlm.nih.gov/pubmed/30279647
http://dx.doi.org/10.3389/fnmol.2018.00324

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