Inhibition of DNA Methylation With Zebularine Alters Lipopolysaccharide-Induced Sickness Behavior and Neuroinflammation in Mice

Activity of DNA methyltransferases (DNMTs), the enzymes that catalyze DNA methylation, is dynamically regulated in the brain. DNMT inhibitors alter DNA methylation globally in the brain and at individual neural plasticity-associated genes, but how DNMT inhibitors centrally influence lipopolysacchari...

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Detalles Bibliográficos
Autores principales: Matt, Stephanie M., Zimmerman, Jalisa D., Lawson, Marcus A., Bustamante, Angela C., Uddin, Monica, Johnson, Rodney W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153314/
https://www.ncbi.nlm.nih.gov/pubmed/30279646
http://dx.doi.org/10.3389/fnins.2018.00636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153314/
https://www.ncbi.nlm.nih.gov/pubmed/30279646
http://dx.doi.org/10.3389/fnins.2018.00636

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