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Prioritized High-Confidence Risk Genes for Intellectual Disability Reveal Molecular Convergence During Brain Development

Dissecting the genetic susceptibility to intellectual disability (ID) based on de novo mutations (DNMs) will aid our understanding of the neurobiological and genetic basis of ID. In this study, we identify 63 high-confidence ID genes with q-values < 0.1 based on four background DNM rates and codi...

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Detalles Bibliográficos
Autores principales: Liu, Zhenwei, Zhang, Na, Zhang, Yu, Du, Yaoqiang, Zhang, Tao, Li, Zhongshan, Wu, Jinyu, Wang, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153320/
https://www.ncbi.nlm.nih.gov/pubmed/30279698
http://dx.doi.org/10.3389/fgene.2018.00349