Real‐time examination of cAMP activity at relaxin family peptide receptors using a BRET‐based biosensor

Relaxin family peptide (RXFPs) 1‐4 receptors modulate the activity of cyclic adenosine monophosphate (cAMP) to produce a range of physiological functions. RXFP1 and RXFP2 increase cAMP via Gα(s), whereas RXFP3 and RXFP4 inhibit cAMP via Gα(i/o). RXFP1 also shows a delayed increase in cAMP downstream...

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Detalles Bibliográficos
Autores principales: Valkovic, Adam L., Leckey, Miranda B., Whitehead, Alice R., Hossain, Mohammed A., Inoue, Asuka, Kocan, Martina, Bathgate, Ross A. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153321/
https://www.ncbi.nlm.nih.gov/pubmed/30263124
http://dx.doi.org/10.1002/prp2.432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153321/
https://www.ncbi.nlm.nih.gov/pubmed/30263124
http://dx.doi.org/10.1002/prp2.432

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