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A paternal methyl donor depleted diet leads to increased anxiety- and depression-like behavior in adult rat offspring

Epigenetic mechanisms such as DNA methylation elicit lasting changes in gene expression and likely mediate gene–environment interactions that shape brain development, behavior, and emotional health. Myriad environmental factors influence DNA methylation, including methyl donor content in the paterna...

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Detalles Bibliográficos
Autores principales: McCoy, Chelsea R., Jackson, Nateka L., Brewer, Rachel L., Moughnyeh, Mohamad M., Smith, Daniel L., Clinton, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153370/
https://www.ncbi.nlm.nih.gov/pubmed/29945927
http://dx.doi.org/10.1042/BSR20180730