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A paternal methyl donor depleted diet leads to increased anxiety- and depression-like behavior in adult rat offspring
Epigenetic mechanisms such as DNA methylation elicit lasting changes in gene expression and likely mediate gene–environment interactions that shape brain development, behavior, and emotional health. Myriad environmental factors influence DNA methylation, including methyl donor content in the paterna...
Autores principales: | McCoy, Chelsea R., Jackson, Nateka L., Brewer, Rachel L., Moughnyeh, Mohamad M., Smith, Daniel L., Clinton, Sarah M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153370/ https://www.ncbi.nlm.nih.gov/pubmed/29945927 http://dx.doi.org/10.1042/BSR20180730 |
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