Quantitation of paracetamol by liquid chromatography–mass spectrometry in human plasma in support of clinical trial

AIM: Paracetamol is a well-tolerated antipyretic widely used in severe malaria management. The study aimed to develop and validate a rapid LC–MS/MS assay to quantify paracetamol in plasma from patients with severe malaria. MATERIALS & METHODS: Plasma sample was precipitated by organic solvent co...

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Detalles Bibliográficos
Autores principales: Kam, Richard Kin-Ting, Chan, Michael Ho-Ming, Wong, Hiu-Ting, Ghose, Aniruddha, Dondorp, Arjen M, Plewes, Katherine, Tarning, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153454/
https://www.ncbi.nlm.nih.gov/pubmed/30271617
http://dx.doi.org/10.4155/fsoa-2018-0039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153454/
https://www.ncbi.nlm.nih.gov/pubmed/30271617
http://dx.doi.org/10.4155/fsoa-2018-0039

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