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Quantitation of paracetamol by liquid chromatography–mass spectrometry in human plasma in support of clinical trial
AIM: Paracetamol is a well-tolerated antipyretic widely used in severe malaria management. The study aimed to develop and validate a rapid LC–MS/MS assay to quantify paracetamol in plasma from patients with severe malaria. MATERIALS & METHODS: Plasma sample was precipitated by organic solvent co...
Autores principales: | Kam, Richard Kin-Ting, Chan, Michael Ho-Ming, Wong, Hiu-Ting, Ghose, Aniruddha, Dondorp, Arjen M, Plewes, Katherine, Tarning, Joel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153454/ https://www.ncbi.nlm.nih.gov/pubmed/30271617 http://dx.doi.org/10.4155/fsoa-2018-0039 |
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