GD2 ganglioside-binding antibody 14G2a and specific aurora A kinase inhibitor MK-5108 induce autophagy in IMR-32 neuroblastoma cells

The process of autophagy and its role in survival of human neuroblastoma cell cultures was studied upon addition of an anti-GD2 ganglioside (GD2) 14G2a mouse monoclonal antibody (14G2a mAb) and an aurora A kinase specific inhibitor, MK-5108. It was recently shown that combination of these agents sig...

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Detalles Bibliográficos
Autores principales: Durbas, Małgorzata, Pabisz, Paweł, Wawak, Katarzyna, Wiśniewska, Aneta, Boratyn, Elżbieta, Nowak, Iwona, Horwacik, Irena, Woźnicka, Olga, Rokita, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153511/
https://www.ncbi.nlm.nih.gov/pubmed/30027525
http://dx.doi.org/10.1007/s10495-018-1472-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153511/
https://www.ncbi.nlm.nih.gov/pubmed/30027525
http://dx.doi.org/10.1007/s10495-018-1472-9

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