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Using Mendelian Randomization to Decipher Mechanisms of Bone Disease

PURPOSE OF REVIEW: This review summarizes the basic principles of Mendelian randomization (MR) and provides evidence for the causal effect of multiple modifiable factors on bone outcomes. RECENT FINDINGS: Several studies using MR approach have provided support for the causal effect of obesity on bon...

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Detalles Bibliográficos
Autores principales: Trajanoska, Katerina, Rivadeneira, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153565/
https://www.ncbi.nlm.nih.gov/pubmed/30203249
http://dx.doi.org/10.1007/s11914-018-0467-3