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The Impact of Pancreatic Beta Cell Heterogeneity on Type 1 Diabetes Pathogenesis

PURPOSE OF REVIEW: To discuss advances in our understanding of beta-cell heterogeneity and the ramifications of this for type 1 diabetes (T1D) and its therapy. RECENT FINDINGS: A number of studies have challenged the long-standing dogma that the majority of beta cells are eliminated in T1D. As many...

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Detalles Bibliográficos
Autores principales: Benninger, Richard K. P., Dorrell, Craig, Hodson, David J., Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153573/
https://www.ncbi.nlm.nih.gov/pubmed/30251179
http://dx.doi.org/10.1007/s11892-018-1085-2