The geometry of partial fitness orders and an efficient method for detecting genetic interactions

We present an efficient computational approach for detecting genetic interactions from fitness comparison data together with a geometric interpretation using polyhedral cones associated to partial orderings. Genetic interactions are defined by linear forms with integer coefficients in the fitness va...

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Detalles Bibliográficos
Autores principales: Lienkaemper, Caitlin, Lamberti, Lisa, Drain, James, Beerenwinkel, Niko, Gavryushkin, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153669/
https://www.ncbi.nlm.nih.gov/pubmed/29736875
http://dx.doi.org/10.1007/s00285-018-1237-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153669/
https://www.ncbi.nlm.nih.gov/pubmed/29736875
http://dx.doi.org/10.1007/s00285-018-1237-7

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