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Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA

Alpha synuclein (α-syn) is central to the pathogenesis of a group of neurodegenerative disorders known as synucleinopathies, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Aggregation of α-syn is the pathologic hallmark of these disorders and...

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Detalles Bibliográficos
Autores principales: Becker, Katelyn, Wang, Xinhe, Vander Stel, Kayla, Chu, Yaping, Kordower, Jeffrey, Ma, Jiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153717/
https://www.ncbi.nlm.nih.gov/pubmed/29589283
http://dx.doi.org/10.1007/s12035-018-1007-y