Cargando…

Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7

Defects in autophagy and the resulting deposition of protein aggregates have been implicated in aging and neurodegenerative diseases. While gene targeting in the mouse has facilitated the characterization of these processes in different types of neurons, potential roles of autophagy and accumulation...

Descripción completa

Detalles Bibliográficos
Autores principales: Sukseree, Supawadee, László, Lajos, Gruber, Florian, Bergmann, Sophie, Narzt, Marie Sophie, Nagelreiter, Ionela Mariana, Höftberger, Romana, Molnár, Kinga, Rauter, Günther, Birngruber, Thomas, Larue, Lionel, Kovacs, Gabor G., Tschachler, Erwin, Eckhart, Leopold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153718/
https://www.ncbi.nlm.nih.gov/pubmed/29550918
http://dx.doi.org/10.1007/s12035-018-0996-x