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Chemical Synthesis and Characterization of an Equinatoxin II(1–85) Analogue

The chemical synthesis of an 85 residue analogue of the pore-forming protein, Equinatoxin II (EqtII), was achieved. Peptide precursors with over 40 residues were assembled by solid phase synthesis. The EqtII(1–46) fragment was modified to the reactive C-terminal thioester and native chemical ligatio...

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Detalles Bibliográficos
Autores principales: Karas, John A., Sani, Marc-Antoine, Separovic, Frances
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153748/
https://www.ncbi.nlm.nih.gov/pubmed/28358312
http://dx.doi.org/10.3390/molecules22040559