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Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP

Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are highly expressed in tumor cells, as well as in organs involved in absorption and secretion processes, mediating the ATP-dependent efflux of compounds, both endogenous substances and xenobiotics, including drugs. Their expression an...

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Detalles Bibliográficos
Autores principales: Gameiro, Mariline, Silva, Renata, Rocha-Pereira, Carolina, Carmo, Helena, Carvalho, Félix, Bastos, Maria de Lourdes, Remião, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153761/
https://www.ncbi.nlm.nih.gov/pubmed/28397762
http://dx.doi.org/10.3390/molecules22040600