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Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP
Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are highly expressed in tumor cells, as well as in organs involved in absorption and secretion processes, mediating the ATP-dependent efflux of compounds, both endogenous substances and xenobiotics, including drugs. Their expression an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153761/ https://www.ncbi.nlm.nih.gov/pubmed/28397762 http://dx.doi.org/10.3390/molecules22040600 |