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Generation of genetically-engineered animals using engineered endonucleases
The key to successful drug discovery and development is to find the most suitable animal model of human diseases for the preclinical studies. The recent emergence of engineered endonucleases is allowing for efficient and precise genome editing, which can be used to develop potentially useful animal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Pharmaceutical Society of Korea
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153862/ https://www.ncbi.nlm.nih.gov/pubmed/29777358 http://dx.doi.org/10.1007/s12272-018-1037-z |