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High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis

Collagen synthesis is severely diminished in osteoarthritis; thus, enhancing it may help the regeneration of cartilage. This requires large amounts of glycine, proline and lysine. Previous works of our group have shown that glycine is an essential amino acid, which must be present in the diet in lar...

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Detalles Bibliográficos
Autores principales: de Paz-Lugo, Patricia, Lupiáñez, José Antonio, Meléndez-Hevia, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153947/
https://www.ncbi.nlm.nih.gov/pubmed/30006659
http://dx.doi.org/10.1007/s00726-018-2611-x