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High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis
Collagen synthesis is severely diminished in osteoarthritis; thus, enhancing it may help the regeneration of cartilage. This requires large amounts of glycine, proline and lysine. Previous works of our group have shown that glycine is an essential amino acid, which must be present in the diet in lar...
Autores principales: | de Paz-Lugo, Patricia, Lupiáñez, José Antonio, Meléndez-Hevia, Enrique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153947/ https://www.ncbi.nlm.nih.gov/pubmed/30006659 http://dx.doi.org/10.1007/s00726-018-2611-x |
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