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Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients
BACKGROUND: To deliver efficacious personalised cancer treatment, it is essential to characterise the cellular metabolism as well as the genetic stability of individual tumours. In this study, we describe a new axis between DNA repair and detoxification of aldehyde derivatives with important implica...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153960/ https://www.ncbi.nlm.nih.gov/pubmed/30088263 http://dx.doi.org/10.1007/s13402-018-0390-8 |