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Oral adsorbent AST-120 ameliorates gut environment and protects against the progression of renal impairment in CKD rats

BACKGROUND: Oral charcoal adsorbent AST-120 (AST) is reported to ameliorate renal dysfunction by the absorption of toxic substance in the gut. Recent study revealed that, in CKD, gut environment is disturbed including the decrease in tight junctions and Lactobacillus (Lact). In this study, we examin...

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Detalles Bibliográficos
Autores principales: Yoshifuji, Ayumi, Wakino, Shu, Irie, Junichiro, Matsui, Ayumi, Hasegawa, Kazuhiro, Tokuyama, Hirobumi, Hayashi, Koichi, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154091/
https://www.ncbi.nlm.nih.gov/pubmed/29675795
http://dx.doi.org/10.1007/s10157-018-1577-z