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Generation and Applications of a DNA Aptamer against Gremlin-1

Gremlin-1, a highly conserved glycosylated and phosphorylated secretory protein, plays important roles in diverse biological processes including early embryonic development, fibrosis, tumorigenesis, and renal pathophysiology. Aptamers, which are RNA or DNA single-stranded oligonucleotides capable of...

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Detalles Bibliográficos
Autores principales: Li, Qian, Huo, Yongwei, Guo, Yonghong, Zheng, Xiaoyan, Sun, Wengang, Hao, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154100/
https://www.ncbi.nlm.nih.gov/pubmed/28452949
http://dx.doi.org/10.3390/molecules22050706