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Synthesis of Aminoglycoside-2′-O-Methyl Oligoribonucleotide Fusions
Phosphoramidite building blocks of ribostamycin (3 and 4), that may be incorporated at any position of the oligonucleotide sequence, were synthesized. The building blocks, together with a previously described neomycin-modified solid support, were applied for the preparation of aminoglycoside-2′-O-me...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154110/ https://www.ncbi.nlm.nih.gov/pubmed/28481305 http://dx.doi.org/10.3390/molecules22050760 |