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Synthesis of Aminoglycoside-2′-O-Methyl Oligoribonucleotide Fusions

Phosphoramidite building blocks of ribostamycin (3 and 4), that may be incorporated at any position of the oligonucleotide sequence, were synthesized. The building blocks, together with a previously described neomycin-modified solid support, were applied for the preparation of aminoglycoside-2′-O-me...

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Detalles Bibliográficos
Autores principales: Granqvist, Lotta, Kraszewski, Andrzej, Tähtinen, Ville, Virta, Pasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154110/
https://www.ncbi.nlm.nih.gov/pubmed/28481305
http://dx.doi.org/10.3390/molecules22050760