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The Protective Effect of Repeated 1MeTIQ Administration on the Lactacystin-Induced Impairment of Dopamine Release and Decline in TH Level in the Rat Brain

Parkinson’s disease (PD) is a neurodegenerative disorder of the central nervous system (CNS) caused by a progressive loss of nigrostriatal dopaminergic neurons. Dysfunction of the ubiquitin-proteasome system (UPS) plays an important role in the pathogenesis of PD. Intranigral administration of the U...

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Detalles Bibliográficos
Autores principales: Wąsik, Agnieszka, Romańska, Irena, Zelek-Molik, Agnieszka, Nalepa, Irena, Antkiewicz-Michaluk, Lucyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154174/
https://www.ncbi.nlm.nih.gov/pubmed/30129004
http://dx.doi.org/10.1007/s12640-018-9939-6