Protease-Activatable Scaffold Proteins as Versatile Molecular Hubs in Synthetic Signaling Networks

[Image: see text] Protease signaling and scaffold-induced control of protein–protein interactions represent two important mechanisms for intracellular signaling. Here we report a generic and modular approach to control the activity of scaffolding proteins by protease activity, creating versatile mol...

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Detalles Bibliográficos
Autores principales: Aper, Stijn J. A., den Hamer, Anniek, Wouters, Simone F. A., Lemmens, Lenne J. M., Ottmann, Christian, Brunsveld, Luc, Merkx, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154215/
https://www.ncbi.nlm.nih.gov/pubmed/30125482
http://dx.doi.org/10.1021/acssynbio.8b00217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154215/
https://www.ncbi.nlm.nih.gov/pubmed/30125482
http://dx.doi.org/10.1021/acssynbio.8b00217

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