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Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies
[Image: see text] Since their description in the late 1990s, Human Artificial Chromosomes (HACs) bearing functional kinetochores have been considered as promising systems for gene delivery and expression. More recently a HAC assembled from a synthetic alphoid DNA array has been exploited in studies...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154217/ https://www.ncbi.nlm.nih.gov/pubmed/30075081 http://dx.doi.org/10.1021/acssynbio.8b00230 |