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Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies

[Image: see text] Since their description in the late 1990s, Human Artificial Chromosomes (HACs) bearing functional kinetochores have been considered as promising systems for gene delivery and expression. More recently a HAC assembled from a synthetic alphoid DNA array has been exploited in studies...

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Detalles Bibliográficos
Autores principales:	Kouprina, Natalay, Petrov, Nikolai, Molina, Oscar, Liskovykh, Mikhail, Pesenti, Elisa, Ohzeki, Jun-ichirou, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154217/ https://www.ncbi.nlm.nih.gov/pubmed/30075081 http://dx.doi.org/10.1021/acssynbio.8b00230

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