Evaluating the current state of Mendelian randomization studies: a protocol for a systematic review on methodological and clinical aspects using neurodegenerative disorders as outcome

BACKGROUND: Mendelian randomization (MR) is fast becoming a popular method to judge causality from routinely conducted observational studies. However, stringent underlying statistical assumptions, missing biological information, and high sample size requirement might make it prone to misuse. Further...

Descripción completa

Detalles Bibliográficos
Autores principales: Grover, Sandeep, Del Greco M., Fabiola, König, Inke R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154408/
https://www.ncbi.nlm.nih.gov/pubmed/30249280
http://dx.doi.org/10.1186/s13643-018-0809-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154408/
https://www.ncbi.nlm.nih.gov/pubmed/30249280
http://dx.doi.org/10.1186/s13643-018-0809-3

Ejemplares similares