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Evaluating the current state of Mendelian randomization studies: a protocol for a systematic review on methodological and clinical aspects using neurodegenerative disorders as outcome

BACKGROUND: Mendelian randomization (MR) is fast becoming a popular method to judge causality from routinely conducted observational studies. However, stringent underlying statistical assumptions, missing biological information, and high sample size requirement might make it prone to misuse. Further...

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Detalles Bibliográficos
Autores principales:	Grover, Sandeep, Del Greco M., Fabiola, König, Inke R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154408/ https://www.ncbi.nlm.nih.gov/pubmed/30249280 http://dx.doi.org/10.1186/s13643-018-0809-3

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