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Analytic and clinical validity of thyroid nodule mutational profiling using droplet digital polymerase chain reaction

BACKGROUND: Recent guidelines for the management of thyroid nodules incorporate mutation testing as an adjunct for surgical decision-making, however current tests are costly with limited accuracy. Droplet digital PCR (ddPCR) is an ultrasensitive method of nucleic acid detection that is particularly...

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Detalles Bibliográficos
Autores principales: Biron, Vincent L., Matkin, Ashlee, Kostiuk, Morris, Williams, Jordana, Cote, David W., Harris, Jeffrey, Seikaly, Hadi, O’Connell, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154415/
https://www.ncbi.nlm.nih.gov/pubmed/30249281
http://dx.doi.org/10.1186/s40463-018-0299-2