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Analytic and clinical validity of thyroid nodule mutational profiling using droplet digital polymerase chain reaction
BACKGROUND: Recent guidelines for the management of thyroid nodules incorporate mutation testing as an adjunct for surgical decision-making, however current tests are costly with limited accuracy. Droplet digital PCR (ddPCR) is an ultrasensitive method of nucleic acid detection that is particularly...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154415/ https://www.ncbi.nlm.nih.gov/pubmed/30249281 http://dx.doi.org/10.1186/s40463-018-0299-2 |