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SPAG5 promotes hepatocellular carcinoma progression by downregulating SCARA5 through modifying β-catenin degradation

BACKGROUND: The sperm-associated antigen 5 (SPAG5) plays a key role in controlling various cellular phenomena, including cell cycle progression and proliferation. However, the role of SPAG5 in hepatocellular carcinoma (HCC) remains unknown. METHODS: This study investigated the function and clinical...

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Detalles Bibliográficos
Autores principales: Liu, Hongliang, Hu, Junwen, Wei, Ran, Zhou, Longfei, Pan, Hua, Zhu, Hongchao, Huang, Mingwen, Luo, Jun, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154423/
https://www.ncbi.nlm.nih.gov/pubmed/30249289
http://dx.doi.org/10.1186/s13046-018-0891-3