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TLR4/MyD88 -mediated CCL2 production by lipopolysaccharide (endotoxin): Implications for metabolic inflammation

BACKGROUND: Obese human and mice were reported to have higher circularity endotoxin (LPS) levels as compared to their lean counter parts. The current study was aimed to reveal the molecular mechanisms underlying the LPS mediated induction of CCL2 in human monocytes/macrophages. METHODS: Human monocy...

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Detalles Bibliográficos
Autores principales: Akhter, Nadeem, Hasan, Amal, Shenouda, Steve, Wilson, Ajit, Kochumon, Shihab, Ali, Shamsha, Tuomilehto, Jaakko, Sindhu, Sardar, Ahmad, Rasheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154519/
https://www.ncbi.nlm.nih.gov/pubmed/30288388
http://dx.doi.org/10.1007/s40200-018-0341-y