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Mesoporous Silica Nanoparticles as Carriers for Intracellular Delivery of Nucleic Acids and Subsequent Therapeutic Applications

Nucleic acids, including DNA, microRNA (miRNA), small interfering RNA (siRNA), and antisense oligonucleotide (ASO), are powerful gene regulators, which have been demonstrated as promising drug candidates for therapeutic treatments. Nevertheless, poor cellular membrane permeability and serum stabilit...

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Detalles Bibliográficos
Autores principales: Cha, Wenzhang, Fan, Rengen, Miao, Yufeng, Zhou, Yong, Qin, Chenglin, Shan, Xiangxiang, Wan, Xinqiang, Li, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154527/
https://www.ncbi.nlm.nih.gov/pubmed/28492505
http://dx.doi.org/10.3390/molecules22050782