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The Hypnotic, Anxiolytic, and Antinociceptive Profile of a Novel µ-Opioid Agonist

5′-4-Alkyl/aryl-1H-1,2,3-triazole derivatives PILAB 1–12 were synthesized and a pharmacological screening of these derivatives was performed to identify a possible effect on the Central Nervous System (CNS) and to explore the associated mechanisms of action. The mice received a peritoneal injection...

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Detalles Bibliográficos
Autores principales: Montes, Guilherme Carneiro, da Silva, Bianca Nascimento Monteiro, Rezende, Bismarck, Sudo, Roberto Takashi, Ferreira, Vitor Francisco, de Carvalho da Silva, Fernando, da Cunha Pinto, Angelo, da Silva, Bárbara Vasconcellos, Zapata-Sudo, Gisele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154531/
https://www.ncbi.nlm.nih.gov/pubmed/28509855
http://dx.doi.org/10.3390/molecules22050800