Synthesis and Antiproliferative Activity of Novel All-Trans-Retinoic Acid-Podophyllotoxin Conjugate towards Human Gastric Cancer Cells

With the purpose of creating a multifunctional drug for gastric cancer treatment, a novel all-trans-retinoic acid (ATRA) conjugate with podophyllotoxin (PPT) was designed and synthesized, and its in vitro antiproliferative activity was evaluated against human gastric cancer cell lines using CCK-8 as...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Wang, Jing, Liu, Lai, Zheng, Chengyue, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154554/
https://www.ncbi.nlm.nih.gov/pubmed/28420180
http://dx.doi.org/10.3390/molecules22040628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154554/
https://www.ncbi.nlm.nih.gov/pubmed/28420180
http://dx.doi.org/10.3390/molecules22040628

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