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Synthesis and Antiproliferative Activity of Novel All-Trans-Retinoic Acid-Podophyllotoxin Conjugate towards Human Gastric Cancer Cells

With the purpose of creating a multifunctional drug for gastric cancer treatment, a novel all-trans-retinoic acid (ATRA) conjugate with podophyllotoxin (PPT) was designed and synthesized, and its in vitro antiproliferative activity was evaluated against human gastric cancer cell lines using CCK-8 as...

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Detalles Bibliográficos
Autores principales:	Zhang, Lei, Wang, Jing, Liu, Lai, Zheng, Chengyue, Wang, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154554/ https://www.ncbi.nlm.nih.gov/pubmed/28420180 http://dx.doi.org/10.3390/molecules22040628

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