Development of Optimized Inhibitor RNAs Allowing Multisite-Targeting of the HCV Genome

Engineered multivalent drugs are promising candidates for fighting infection by highly variable viruses, such as HCV. The combination into a single molecule of more than one inhibitory domain, each with its own target specificity and even a different mechanism of action, results in drugs with potent...

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Detalles Bibliográficos
Autores principales: Romero-López, Cristina, Lahlali, Thomas, Berzal-Herranz, Beatriz, Berzal-Herranz, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154567/
https://www.ncbi.nlm.nih.gov/pubmed/28531161
http://dx.doi.org/10.3390/molecules22050861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154567/
https://www.ncbi.nlm.nih.gov/pubmed/28531161
http://dx.doi.org/10.3390/molecules22050861

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