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Development of Optimized Inhibitor RNAs Allowing Multisite-Targeting of the HCV Genome
Engineered multivalent drugs are promising candidates for fighting infection by highly variable viruses, such as HCV. The combination into a single molecule of more than one inhibitory domain, each with its own target specificity and even a different mechanism of action, results in drugs with potent...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154567/ https://www.ncbi.nlm.nih.gov/pubmed/28531161 http://dx.doi.org/10.3390/molecules22050861 |