Design, Synthesis and Anti-Proliferative Activities of 2,6-Substituted Thieno[3,2-d]pyrimidine Derivatives Containing Electrophilic Warheads

Thieno[3,2-d]pyrimidine as an effective pharmacophore has been extensively studied. However, its 2,6-substituted derivatives are rarely reported. In the present study, eighteen 2,6-substituted thieno[3,2-d]pyrimidine derivatives containing electrophilic warheads were designed based on the first know...

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Detalles Bibliográficos
Autores principales: Zhang, Qiumeng, Hu, Zonglong, Shen, Qianqian, Chen, Yi, Lu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154568/
https://www.ncbi.nlm.nih.gov/pubmed/28498316
http://dx.doi.org/10.3390/molecules22050788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154568/
https://www.ncbi.nlm.nih.gov/pubmed/28498316
http://dx.doi.org/10.3390/molecules22050788

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