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Multi-Anti-Parasitic Activity of Arylidene Ketones and Thiazolidene Hydrazines against Trypanosoma cruzi and Leishmania spp.

A series of fifty arylideneketones and thiazolidenehydrazines was evaluated against Leishmania infantum and Leishmania braziliensis. Furthermore, new simplified thiazolidenehydrazine derivatives were evaluated against Trypanosoma cruzi. The cytotoxicity of the active compounds on non-infected fibrob...

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Detalles Bibliográficos
Autores principales: Álvarez, Guzmán, Perdomo, Cintya, Coronel, Cathia, Aguilera, Elena, Varela, Javier, Aparicio, Gonzalo, Zolessi, Flavio R., Cabrera, Nallely, Vega, Celeste, Rolón, Miriam, Rojas de Arias, Antonieta, Pérez-Montfort, Ruy, Cerecetto, Hugo, González, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154605/
https://www.ncbi.nlm.nih.gov/pubmed/28481276
http://dx.doi.org/10.3390/molecules22050709