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Adenosine A1 and A2A Receptors in the Brain: Current Research and Their Role in Neurodegeneration

The inhibitory adenosine A1 receptor (A1R) and excitatory A2A receptor (A2AR) are predominantly expressed in the brain. Whereas the A2AR has been implicated in normal aging and enhancing neurotoxicity in multiple neurodegenerative diseases, the inhibitory A1R has traditionally been ascribed to have...

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Detalles Bibliográficos
Autores principales: Stockwell, Jocelyn, Jakova, Elisabet, Cayabyab, Francisco S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154612/
https://www.ncbi.nlm.nih.gov/pubmed/28441750
http://dx.doi.org/10.3390/molecules22040676