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Protein Stability and Unfolding Following Glycine Radical Formation

Glycine (Gly) residues are particularly susceptible to hydrogen abstraction; which results in the formation of the capto-dative stabilized C(α)-centered Gly radical (GLR) on the protein backbone. We examined the effect of GLR formation on the structure of the Trp cage; tryptophan zipper; and the vil...

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Detalles Bibliográficos
Autores principales: Owen, Michael C., Csizmadia, Imre G., Viskolcz, Béla, Strodel, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154654/
https://www.ncbi.nlm.nih.gov/pubmed/28422069
http://dx.doi.org/10.3390/molecules22040655