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Protein Stability and Unfolding Following Glycine Radical Formation
Glycine (Gly) residues are particularly susceptible to hydrogen abstraction; which results in the formation of the capto-dative stabilized C(α)-centered Gly radical (GLR) on the protein backbone. We examined the effect of GLR formation on the structure of the Trp cage; tryptophan zipper; and the vil...
Autores principales: | Owen, Michael C., Csizmadia, Imre G., Viskolcz, Béla, Strodel, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154654/ https://www.ncbi.nlm.nih.gov/pubmed/28422069 http://dx.doi.org/10.3390/molecules22040655 |
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