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TCS2 Increases Olaquindox-Induced Apoptosis by Upregulation of ROS Production and Downregulation of Autophagy in HEK293 Cells

Olaquindox, a feed additive, has drawn public attention due to its potential mutagenicity, genotoxicity, hepatoxicity and nephrotoxicity. The purpose of this study was to investigate the role of tuberous sclerosis complex (TSC2) pathways in olaquindox-induced autophagy in human embryonic kidney 293...

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Detalles Bibliográficos
Autores principales: Li, Daowen, Zhao, Kena, Yang, Xiayun, Xiao, Xilong, Tang, Shusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154664/
https://www.ncbi.nlm.nih.gov/pubmed/28387735
http://dx.doi.org/10.3390/molecules22040595