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The epigenetic mechanisms of nanotopography-guided osteogenic differentiation of mesenchymal stem cells via high-throughput transcriptome sequencing
BACKGROUND: Nanotopography directs stem cell fate; however, the underlying mechanisms, especially those at the epigenetic level, remain vague. The TiO(2)-nanotube array, a classical example of nanotopography, is a good model to investigate topography–cell interactions because of its good controllabi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154708/ https://www.ncbi.nlm.nih.gov/pubmed/30271150 http://dx.doi.org/10.2147/IJN.S168928 |