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Deepened cellular/subcellular interface penetration and enhanced antitumor efficacy of cyclic peptidic ligand-decorated accelerating active targeted nanomedicines

INTRODUCTION: Acceleration and improvement of penetration across cell-membrane interfaces of active targeted nanotherapeutics into tumor cells would improve tumor-therapy efficacy by overcoming the issue of poor drug penetration. Cell-penetrating peptides, especially synthetic polyarginine, have sho...

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Detalles Bibliográficos
Autores principales: Shi, Nian-Qiu, Li, Yan, Zhang, Yong, Li, Zheng-Qiang, Qi, Xian-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154709/
https://www.ncbi.nlm.nih.gov/pubmed/30271146
http://dx.doi.org/10.2147/IJN.S172556