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Cytokine release syndrome: grading, modeling, and new therapy

Genetically modified T cells that express a chimeric antigen receptor (CAR) are opening a new frontier in cancer immunotherapy. CAR T cells currently are in clinical trials for many cancer types. Cytokine release syndrome (CRS) and neurotoxicities (CAR-related encephalopathy syndrome, CRES) are majo...

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Detalles Bibliográficos
Autores principales: Liu, Delong, Zhao, Juanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154787/
https://www.ncbi.nlm.nih.gov/pubmed/30249264
http://dx.doi.org/10.1186/s13045-018-0653-x