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CDK4, a new metabolic sensor that antagonizes AMPK

Cyclin-dependent kinase 4 (CDK4) is a positive regulator of cell cycle progression, however, there is growing evidence demonstrating that its function exceeds the control of cell division. Here we show that CDK4 is an important regulator of cellular substrate utilization through direct inhibition of...

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Detalles Bibliográficos
Autores principales: Fajas, L., Lopez-Mejia, I. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154832/
https://www.ncbi.nlm.nih.gov/pubmed/30263936
http://dx.doi.org/10.1080/23723556.2017.1409862